Miltenyi Biotec B.V. & Co. KG 170-081-055 CD3-PE (Clone REA613)

REA613 recognizes the human CD3 antigen, a single-pass type I membrane protein, also known as Leu4. CD3 is present on mature human T cells, thymocytes, a subset of NK cells, and on Purkinje cells in cerebellum. It is associated with the T cell receptor (TCR) and is responsible for its signal transduction. The CD3 antigen is a complex of five invariable chains: gamma, delta, epsilon, zeta, and eta. The epitope recognized by the antibody is located on the epsilon-chain of the CD3 complex. Additional information: Clone REA613 displays negligible binding to Fc receptors.