The Modified Wright and Modified Wright-Giemsa Stain Packs are reagent systems designed for optimal performance on Hematek® slide stainers and used for differential staining of blood films. These systems consist of a modified polychrome methylene blue- eosin stain and are based on the original stain proposed by Dmitri Romanowsky (Romanowsky, D. [1891] St. Petersb. Med. Wschr., 16, 297-307

The Modified Wright and Modified Wright-Giemsa Stain Packs are reagent systems designed for optimal performance on Hematek® slide stainers and used for differential staining of blood films. These systems consist of a modified polychrome methylene blue- eosin stain and are based on the original stain proposed by Dmitri Romanowsky (Romanowsky, D. [1891] St. Petersb. Med. Wschr., 16, 297-307

Hematology stains are typically mixtures of several thiazin dyes in a methanol solvent. Ionic and non-ionic forces are involved in the binding of the dyes. The negatively charged phosphoric acid groups of DNA attract the purple polychromatic cationic dyes to the nuclei. The blue basophilic granules are stained by the polychromatic cationic dyes. Cationic cellular components, such as the erythrocytes and eosinophilic granules, are stained by the red and pink anionic dyes. The buffers used in the staining procedure liberate and activate dye ions allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solution and/or buffer is a critical factor. The Wright, Wright-Giemsa, Giemsa, May-Grunwald and Jenner stains all rely on a separate buffer solution to control the pH of the reaction, whereas the buffered versions are referred to as “one-step” and have the buffering component already in the staining solution. There are pros and cons to each type of hematology stain although they all contain the thiazin dyes which control the coloration of the nuclear cell components. The single solutions with buffer included generally present more precipitate and the cellular detail is not defined as well as using separate stain and buffer solutions. This kit contains three 500ml bottles of Wright Giemsa stain, pH 6.8 Buffer and a Rinse solution intended to be used as a system per the instructions for use.

Hematology stains are typically mixtures of several thiazin dyes in a methanol solvent. Ionic and non-ionic forces are involved in the binding of the dyes. The negatively charged phosphoric acid groups of DNA attract the purple polychromatic cationic dyes to the nuclei. The blue basophilic granules are stained by the polychromatic cationic dyes. Cationic cellular components, such as the erythrocytes and eosinophilic granules, are stained by the red and pink anionic dyes. The buffers used in the staining procedure liberate and activate dye ions allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solution and/or buffer is a critical factor. The Wright, Wright-Giemsa, Giemsa, May-Grunwald and Jenner stains all rely on a separate buffer solution to control the pH of the reaction, whereas the buffered versions are referred to as “one-step” and have the buffering component already in the staining solution. There are pros and cons to each type of hematology stain although they all contain the thiazin dyes which control the coloration of the nuclear cell components. The single solutions with buffer included generally present more precipitate and the cellular detail is not defined as well as using separate stain and buffer solutions. This kit contains three 500ml bottles of Wright Giemsa stain, pH 6.8 Buffer and a Rinse solution intended to be used as a system per the instructions for use.

The Three-Step Stain Set is comprised of three components: a methanol fixative (Fixative), an aqueous eosin solution (Solution A), and an aqueous methylene blue/azure A solution (Solution B). The staining solutions consist of xanthene and thiazine dyes, exhibiting both anionic and cationic properties, respectively. Cationic cellular components, such as erythrocytes and eosinophilic granules, share an affinity for the anionic dye of Solution A. The negatively charged phosphate groups of DNA and basophilic granules of the cytoplasm have an affinity for the polychromatic cationic dyes of Solution B. The aqueous stain formulations function to dissociate and activate the dye ions, allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solutions is a critical factor

The Three-Step Stain Set is comprised of three components: a methanol fixative (Fixative), an aqueous eosin solution (Solution A), and an aqueous methylene blue/azure A solution (Solution B). The staining solutions consist of xanthene and thiazine dyes, exhibiting both anionic and cationic properties, respectively. Cationic cellular components, such as erythrocytes and eosinophilic granules, share an affinity for the anionic dye of Solution A. The negatively charged phosphate groups of DNA and basophilic granules of the cytoplasm have an affinity for the polychromatic cationic dyes of Solution B. The aqueous stain formulations function to dissociate and activate the dye ions, allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solutions is a critical factor

The Three-Step Stain Set is comprised of three components: a methanol fixative (Fixative), an aqueous eosin solution (Solution A), and an aqueous methylene blue/azure A solution (Solution B). The staining solutions consist of xanthene and thiazine dyes, exhibiting both anionic and cationic properties, respectively. Cationic cellular components, such as erythrocytes and eosinophilic granules, share an affinity for the anionic dye of Solution A. The negatively charged phosphate groups of DNA and basophilic granules of the cytoplasm have an affinity for the polychromatic cationic dyes of Solution B. The aqueous stain formulations function to dissociate and activate the dye ions, allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solutions is a critical factor

The Three-Step Stain Set is comprised of three components: a methanol fixative (Fixative), an aqueous eosin solution (Solution A), and an aqueous methylene blue/azure A solution (Solution B). The staining solutions consist of xanthene and thiazine dyes, exhibiting both anionic and cationic properties, respectively. Cationic cellular components, such as erythrocytes and eosinophilic granules, share an affinity for the anionic dye of Solution A. The negatively charged phosphate groups of DNA and basophilic granules of the cytoplasm have an affinity for the polychromatic cationic dyes of Solution B. The aqueous stain formulations function to dissociate and activate the dye ions, allowing them to chemically bond with specific cellular components. When staining blood and bone marrow smears, the pH of the staining solutions is a critical factor

Eosin-Y is an acidified, alcoholic counterstain that provides excellent delineation of cytoplasmic components and stains the cytoplasm of muscle, red blood cells, and connective tissue three distinct color hues of pink to red. Eosin-Y provides excellent contrast between cytoplasmic components and the bluish-purple hues of the nuclear chromatin.

Eosin-Y Alcoholic is a ready-to-use alcoholic, acidified counterstain. This product stains the cytoplasm of muscle, red blood cells, and connective tissue three distinct color hues of pink to red. Eosin-Y Alcoholic provides clear cytoplasmic and nuclear contrast.

Eosin-Y Alcoholic is a ready-to-use alcoholic, acidified counterstain. This product stains the cytoplasm of muscle, red blood cells, and connective tissue three distinct color hues of pink to red. Eosin-Y Alcoholic provides clear cytoplasmic and nuclear contrast.

Eosin-Y Alcoholic is a ready-to-use alcoholic, acidified counterstain. This product stains the cytoplasm of muscle, red blood cells, and connective tissue three distinct color hues of pink to red. Eosin-Y Alcoholic provides clear cytoplasmic and nuclear contrast.

Eosin-Y w/ Phloxine is a ready-to-use alcoholic, acidified counterstain to which phloxine B dye has been added. The addition of phloxine B results in a more intense red coloration of connective tissue, especially muscle, as well as better demonstration of inclusion bodies.

Eosin-Y w/ Phloxine is a ready-to-use alcoholic, acidified counterstain to which phloxine B dye has been added. The addition of phloxine B results in a more intense red coloration of connective tissue, especially muscle, as well as better demonstration of inclusion bodies.

Eosin-Y Saturated is an alcohol-based, rapid cytoplasmic stain. It does not contain glacial acetic acid, so its pH is higher (i.e. more neutral) than other alcoholic eosin Y counterstains. This stain will provide intensities similar to other commercially available eosin Y products.

Hematoxylin 7211 is a rapid, progressive hematoxylin. The product is a hybrid between classical Harris and Gill formulations: it provides the classic intensity and hues of a Harris hematoxylin and the rapid progressive qualities of a Gill hematoxylin. Differentiation is not required, but if desired Clarifier 1 should be used. Clarifier 1 will eliminate any background staining that may be caused by the use of excess gelatin or other adhesives in the water bath. Clarifier 2 can be used as well; however, a shorter immersion time is required. Hematoxylin 7211 does not have an affinity for acid mucopolysaccharide (mucin) staining, as do some other hematoxylin formulations. It provides consistent, well-delineated nuclear staining results.

Hematoxylin 1 is a rapid, progressive hematoxylin designed to produce staining characteristics, intensities, and hues similar to Gill 1 & 2 hematoxylins. Hematoxylin 2 is a darker and more color intensive version of the Hematoxylin 1 stain.

Hematoxylin 1 is a rapid, progressive hematoxylin designed to produce staining characteristics, intensities, and hues similar to Gill 1 & 2 hematoxylins. Hematoxylin 2 is a darker and more color intensive version of the Hematoxylin 1 stain.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Gill Hematoxylin 1, 2, and 3 are rapid, progressive hematoxylins that are widely known and respected in the histology and cytology fields. They offer convenience and choice of stain intensity. Gill hematoxylins are ready to use and will provide familiar, consistent, well-delineated results. Stain filtering may be needed to remove sheen caused by oxidation or cells shed off of slides in the cytology staining process. Gill 1 is the least intense stain and is most commonly used in cytology and in special stains. Gill 2 is a moderately intense stain and is most commonly used in histology, with some limited use in cytology. Gill 3 is an intense stain and is exclusively used in histology as well as staining of plastic sections.

Modified Harris Hematoxylin is an acidified, ready-to-use formulation that provides traditional nuclear staining results. Harris hematoxylin procedures require acid alcohol differentiation. The nuclear chromatin and cytoplasm are overstained and the acid alcohol is used to destain the cytoplasm and to remove excess stain from the nucleus. Staining times are typically in the 5-minute range. Epredia Differentiating Solution is recommended for use with Modified Harris Hematoxylin

Modified Harris Hematoxylin is an acidified, ready-to-use formulation that provides traditional nuclear staining results. Harris hematoxylin procedures require acid alcohol differentiation. The nuclear chromatin and cytoplasm are overstained and the acid alcohol is used to destain the cytoplasm and to remove excess stain from the nucleus. Staining times are typically in the 5-minute range. Epredia Differentiating Solution is recommended for use with Modified Harris Hematoxylin

Modified Harris Hematoxylin is an acidified, ready-to-use formulation that provides traditional nuclear staining results. Harris hematoxylin procedures require acid alcohol differentiation. The nuclear chromatin and cytoplasm are overstained and the acid alcohol is used to destain the cytoplasm and to remove excess stain from the nucleus. Staining times are typically in the 5-minute range. Epredia Differentiating Solution is recommended for use with Modified Harris Hematoxylin

Bluing Reagent is intended to be used as an aid in hematoxylin staining for the diagnosis of general pathology specimens. Bluing Reagent is a buffered alkaline rinse that shifts the final hue of hematoxylin from reddish-blue to traditional blue-purple. Unlike ammonia water and lithium carbonate, Bluing Reagent inhibits pH changes that can adversely affect nuclear detail and “crispness”.

Bluing Reagent is intended to be used as an aid in hematoxylin staining for the diagnosis of general pathology specimens. Bluing Reagent is a buffered alkaline rinse that shifts the final hue of hematoxylin from reddish-blue to traditional blue-purple. Unlike ammonia water and lithium carbonate, Bluing Reagent inhibits pH changes that can adversely affect nuclear detail and “crispness”.

Clarifier™ 1 is a reagent designed to eliminate background staining sometimes caused by excessive adhesives in the water bath such as gelatin. Clarifier™ 1 selectively removes hematoxylin staining from excess adhesive without affecting nuclear staining. This product is only effective with progressive staining and should not be used with regressive stains. Clarifier™ 1 is designed for use after staining with progressive hematoxylins. After tissues have been sufficiently stained with a progressive hematoxylin, slides are removed from the stain and excess hematoxylin is removed by rinsing the sections in water. The sections are then placed into Clarifier™ 1 for 30 seconds to 1 minute. A 1-minute water rinse should follow as this stops the reaction and rinses excess acid from the tissue section. If Clarifier™ 1 is not successful in removing the background staining, use Clarifier™ 2 in its place with a possible time reduction.

Clarifier™ 2 is an aqueous glacial acetic acid rinse designed to eliminate background staining sometimes caused by excessive adhesives in the water bath such as gelatin. Clarifier™ 2 selectively removes hematoxylin staining from excess adhesive without affecting nuclear staining. This product is only effective with progressive staining an should not be used with regressive stains. Clarifier 2 was designed to be used in histology only. Clarifier™ 2 is designed for use after staining with progressive hematoxylins. After tissues have been sufficiently stained with a progressive hematoxylin, slides are removed from the stain and excess hematoxylin is removed by rinsing the sections in water. The sections are then placed into Clarifier™ 2 for 20 seconds to 40 seconds. A 1-minute water rinse should follow as this stops the reaction and rinses excess acid from the tissue section.

Differentiating Solution is intended to be used as an aid in hematoxylin staining for the diagnosis of general pathology specimens. Differentiating Solution is an acid alcohol solution to be used with the Modified Harris Hematoxylin. It is formulated as a standard 1% hydrochloric acid in 70% alcohol solution and will provide consistent differentiation results. Differentiating Solution’s mode of action is that it aggressively reacts with the tissue dye-lake complex in nuclear chromatin, resulting in the removal of the stain. Due to weak bonding in the cytoplasm, hematoxylin in this area is also easily and completely removed. Generally, two to four quick dips will be adequate for differentiation when using Differentiating Solution, followed by a 1-minute water rinse to stop the reaction and fully remove the acid from the tissue.

Differentiating Solution is intended to be used as an aid in hematoxylin staining for the diagnosis of general pathology specimens. Differentiating Solution is an acid alcohol solution to be used with the Modified Harris Hematoxylin. It is formulated as a standard 1% hydrochloric acid in 70% alcohol solution and will provide consistent differentiation results. Differentiating Solution’s mode of action is that it aggressively reacts with the tissue dye-lake complex in nuclear chromatin, resulting in the removal of the stain. Due to weak bonding in the cytoplasm, hematoxylin in this area is also easily and completely removed. Generally, two to four quick dips will be adequate for differentiation when using Differentiating Solution, followed by a 1-minute water rinse to stop the reaction and fully remove the acid from the tissue.

For the quantitative determination of cross-linked fibrin degradation products (D-dimers) in human plasma on Siemens Sysmex® Coagulation Systems

For the quantitative determination of cross-linked fibrin degradation products (D-dimers) in human plasma on Siemens Sysmex® Coagulation Systems

Supplementary Reagent for coagulation tests

Determination of the activated partial thromboplastin time (APTT) in citrated human plasma

Determination of the activated partial thromboplastin time (APTT) in citrated human plasma

Assayed control to monitor the performance of Factor V Leiden assay in the pathological range

Calibrators for the assay of fibrinogen by the method of Clauss using Multifibren U

Coagulation test for the quantitative determination of protein C activity in human plasma

Supplementary Reagent for coagulation tests

Assayed control used to monitor the performance of coagulation assays in the normal range

For the determination of the activity of coagulation factor V in human plasma by coagulometric methods

For the determination of the activity of coagulation factor XII in human plasma by coagulometric methods

For the determination of the activity of coagulation factor II (prothrombin) in human plasma by coagulometric methods

For the determination of the activity of coagulation factor VII in human plasma by coagulometric methods

For the determination of the activity of coagulation factor VIII in human plasma by coagulometric methods

For the determination of the activity of coagulation factor IX in human plasma by coagulometric methods

The Uri-Trak® 120 M Urine Analyzer is intended for use in conjunction with the Uri-Chek® 10SG Urinalysis Reagent Strips for the semi-quantitative detection of the following analytes in urine: Glucose, Bilirubin, Ketone (Acetoacetic acid), Specific Gravity, pH, Blood, Protein, Urobilinogen, Leukocytes, as well as the qualitative detection of Nitrite. The instrument is intended for professional, in vitro diagnostic use only. The measurement can be used in general evaluation of health, and aids in the diagnosis and monitoring of metabolic or systemic diseases that affect kidney function, endocrine disorders and diseases or disorders of the urinary tract.